ĐẶC ĐIỂM LÂM SÀNG, CHỨC NĂNG HÔ HẤP VÀ HÌNH ẢNH CẮT LỚP VI TÍNH LỒNG NGỰC ĐỘ PHÂN GIẢI CAO Ở BỆNH NHÂN MẮC BỆNH PHỔI KẼ DO XƠ CỨNG BÌ HỆ THỐNG

Abstract

Objectives: To describe characteristics of clinical, respiratory function, and chest high-resolution CT (HRCT) in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD). Methods: A cross-sectional descriptive study was conducted on 27 SSc-ILD patients treated in National Lung Hospital and Military Hospital 103 from January 2022 to December 2024. Results: Most patients were female (81.5%), with a mean age of 60.3 ± 8.0 years. The common clinical symptoms were dyspnea (88.9%) and cough (77.8%). Fine crackles were the most frequent physical sign (92.6%). Respiratory function tests demonstrated a restrictive ventilatory defect, with a mean %FVC of 62.9 ± 16.0% and %TLC of 60.3 ± 13.2%. On chest HRCT, the predominant patterns included NSIP (70.4%), UIP (18.5%), and OP (11.1%). Ground-glass opacities and reticular opacities were present in most patients. Esophageal dilatation (66.7%) was a frequent associated lesion. Conclusion: SSc-ILD predominantly affects middle-aged women, characterised by cough, dyspnea, and a restrictive ventilatory defect. Common chest HRCT findings incduded NSIP and reticular-ground-glass opacities.